Biology as Poetry: Cell Biology

Bacteriophage Ecology Group

Tyrosine Kinase Receptor

Membrane protein that, upon ligand binding, phosphorylates itself, allowing the now activated to protein to activate other proteins.

Tyrosine kinases phosphorylate specific tyrosine residues in proteins (tyrosine is an amino acid). Tyrosine kinase receptors, upon signal reception, thus phosphorylate their own, specific amino acid residues. The resulting activated receptor protein is then able to activate multiple cytoplasmic proteins, which then continue the signal transduction pathway.

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