Biology as Poetry: Genetics

Bacteriophage Ecology Group

Translation Termination

Release factor binding to the ribosome A site, resulting in a separation of mRNA, polypeptide, and ribosomal subunits.

Release factors bind specifically to stop codons, resulting in translation termination. Note that part of this process involve hydrolysis of the bond connecting the now-completed polypeptide and the tRNA located within the P site (the peptidyl tRNA).

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