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Joining of two compounds in association with the loss of a water molecule between them.
Protein, nucleic acid, and carbohydrate polymers as well as fats are all assembled (polymerized) via a series of dehydration synthesis reactions, which also can be described as condensation reactions or condensation polymerization.
The converse of dehydration synthesis is hydrolysis. Dehydration synthesis, that is, builds build molecules up – at the expense of energy (endergonic reaction) – while hydrolysis breaks breaks molecules apart, liberating energy (exergonic reaction). ATP, for example, is synthesized from ADP and inorganic phosphate via an energy-requiring dehydration synthesis reaction.
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